Illumina Set to Join S&P 500 on September 21
On September 21, Illumina (ILMN) will officially join the S&P 500 index. This change is part of a broader rebalancing that includes Bloom Energy and Everpure replacing Molson Coors Beverage, The Trade Desk, and Builders FirstSource. For investors, this inclusion could lead to increased demand for ILMN shares as passive funds adjust their holdings accordingly. Illumina has seen significant growth in recent years with a 112% return over the past year but underperformed compared to the S&P 500 index by returning just 16% over the last decade. The company's move from mid-cap to large-cap status reflects its substantial business maturity and expansion. In Q2 of 2026, Illumina reported $1.16 billion in revenue with a year-over-year increase of 9.5%. CEO Jacob Thaysen noted this as the fastest growth since his tenure began. The company is also expanding into multiomics through new product lines and strategic acquisitions.
