Cincinnati Children's Receives $38.4 Million NIH Grant Renewal for Congenital Heart Disease Research
Cincinnati Children's Hospital has been awarded a six-year, $38.4 million grant from the National Heart, Lung, and Blood Institute to continue its leadership in the Bench to Bassinet (B2B CHANGE) program focused on congenital heart disease (CHD). The renewed funding will shift the focus of the research from genetic discovery toward long-term clinical outcomes by following participants over time. The grant supports a national longitudinal cohort study that builds upon more than 15 years of federal investment in CHD genomic research, which has enrolled thousands of patients and family members. Cincinnati Children's is now entering its third funding cycle for the program with this latest award, continuing efforts to understand how genetic differences influence health outcomes across lifespans. The B2B CHANGE initiative will re-engage participants through deeper clinical assessments, patient-reported measures, and new biological sample collection. The research aims to improve long-term care strategies by linking genomic data with real-world health results.
Topics: congenital heart disease genetics longitudinal studies NIH funding