Neumora's Depression Drug Fails Phase 3 Trials; enGene to Cut Staff by Half

Shares of Neumora Therapeutics dropped significantly after its depression drug, navacaprant, failed two Phase 3 trials. The company announced it will discontinue development for the drug and shift focus to other therapeutic areas such as obesity, schizophrenia, and Alzheimer’s disease agitation. Meanwhile, enGene plans to lay off half of its workforce and halt enrollment in parts of a gene therapy trial due to financial constraints.

By BioPharma Dive staff Tue, June 16, 2026 at 12:08 PM GMT+3 3 min read · Yahoo Finance ·

Neumora's Depression Drug Fails Phase 3 Trials; enGene to Cut Staff by Half

Tickers: $ENGN $JNJ $NMRA

Topics: depression drug failure layoffs pharmaceuticals

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